Numab raises $22m to advance immuno-oncology antibodies

Credit: Shutterstock.com/ Becky Stares

Swiss biotech, Numab Therapeutics, has raised $22.6 million in Series B financing to advance a portfolio of novel multi-specific antibodies in immuno-oncology.

New investors included 3SBio/Sunshine Guojian, Mitsubishi UFJ Capital Co, and Eisai Co, as well as Numab’s board member Dr Daniel Vasella.

Existing shareholders that participated in Numab’s Series A round also contributed.

Numab will use the proceeds further broaden its proprietary pipeline and accelerate the development for a number of programs towards the clinic.

The company also plans to initiate a clinical trial for its lead oncology program ND021 during the course of 2020.

Numab and Eisai entered into a global research and option agreement to discover and develop a portfolio of multi-specific antibody immunotherapies for cancer in October 2019. In December 2019, Numab added a regional alliance with 3SBio’s subsidiary Sunshine Guojian Pharmaceutical Co to its growing roster of pharmaceutical partnerships.

Multi-specific antibodies have the potential to unlock entirely novel modes-of-action aiming at superior benefit-to-risk profiles relative to conventional cancer immune therapies.

Numab’s proprietary MATCH technology platform represents one of the most versatile and flexible sources for multi-specific antibodies, the company said.

MATCH molecules can incorporate up to six binding specificities in true plug-and-play fashion. The individual antibody Fv building blocks are designed for maximum stability and developability.

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